Respiratory panic disorder subtype and sensitivity to the carbon dioxide challenge test

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Respiratory panic disorder subtype and sensitivity to the carbon dioxide challenge test.

The aim of the present study was to verify the sensitivity to the carbon dioxide (CO2) challenge test of panic disorder (PD) patients with respiratory and nonrespiratory subtypes of the disorder. Our hypothesis is that the respiratory subtype is more sensitive to 35% CO2. Twenty-seven PD subjects with or without agoraphobia were classified into respiratory and nonrespiratory subtypes on the bas...

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The carbon dioxide challenge test in panic disorder: a systematic review of preclinical and clinical research.

This systematic review assesses the current state of clinical and preclinical research on panic disorder (PD) in which the carbon dioxide (CO2) challenge was used as a trigger for panic attacks (PAs). A total of 95 articles published from 1984 to 2012 were selected for inclusion. Some hypotheses for PD evolved greatly due to the reproducibility of PAs in a controlled environment using the safe ...

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Clonidine in respiratory panic disorder subtype.

OBJECTIVE Clonidine, which inhibits locus coeruleus discharge, would seem for theoretical reasons to be a good antipanic drug. Panic disorder (PD) presents a heterogeneous cluster of symptoms and a classification based on subtypes has been suggested and the respiratory symptoms group appears as a distinct subtype. METHOD We report three cases of respiratory PD patients who were successfully t...

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Panic disorder and the respiratory system: clinical subtype and challenge tests.

INTRODUCTION Respiratory changes are associated with anxiety disorders, particularly panic disorder (PD). The stimulation of respiration in PD patients during panic attacks is well documented in the literature, and a number of abnormalities in respiration, such as enhanced CO2 sensitivity, have been detected in PD patients. Investigators hypothesized that there is a fundamental abnormality in t...

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Suffocation and respiratory responses to carbon dioxide and breath holding challenges in individuals with panic disorder.

OBJECTIVE Findings showing that individuals with panic disorder (PD) are prone to experience panic attacks when inhaling CO2-enriched air have given rise to the hypothesis that physiological systems underlying the experience of suffocation may be important in the etiology of PD. In this study, we tested several predictions stemming from this view. METHODS Forty individuals with PD and 32 cont...

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ژورنال

عنوان ژورنال: Brazilian Journal of Medical and Biological Research

سال: 2002

ISSN: 0100-879X

DOI: 10.1590/s0100-879x2002000700004